{Reference Type}: Comparative Study
{Title}: High-sensitivity troponin T release profile in off-pump coronary artery bypass grafting patients with normal postoperative course.
{Author}: Ge W;Gu C;Chen C;Chen W;Cang Z;Wang Y;Shi C;Zhang Y;
{Journal}: BMC Cardiovasc Disord
{Volume}: 18
{Issue}: 1
{Year}: 07 2018 31
{Factor}: 2.174
{DOI}: 10.1186/s12872-018-0893-2
{Abstract}: The aim of the study was to investigate the high-sensitivity troponin T (hs-TnT) release profile in off-pump coronary artery bypass grafting (OPCABG) patients with normal postoperative course.<BR>From January 2015 to October 2016, 398 consecutive OPCABG patients who had normal postoperative courses were enrolled. Blood samples for hs-TnT were collected at several time points and the comparisons among different time points grouped by various factors were further analyzed.<BR>There were 317 male and 81 female patients, with a median age of 64. For 66.1% of the patients, peak hs-TnT occurred at the 24th hour after OPCABG, regardless of the groups divided by different factors. In total, the hs-TnT values were much higher in male group (P = 0.035), in patients who need 5 or more bypass grafts (P = 0.035) and in patients with high-risk EuroSCORE II assessment (P = 0.013). However, we failed to find any significant differences between different age groups (P = 0.129) or among different coronary heart disease classifications (P = 0.191).<BR>The hs-TnT values were affected by various factors and culminated around the first 24 h following OPCABG. It may provide some useful information for future clinical studies of myocardial biomarkers after OPCABG.