{Reference Type}: Journal Article
{Title}: Association of Classic Cardiovascular Risk Factors and Lifestyles With the Cardio-ankle Vascular Index in a General Mediterranean Population.
{Author}: Elosua-Bayés M;Martí-Lluch R;García-Gil MDM;Camós L;Comas-Cufí M;Blanch J;Ponjoan A;Alves-Cabratosa L;Elosua R;Grau M;Marrugat J;Ramos R;
{Journal}: Rev Esp Cardiol (Engl Ed)
{Volume}: 71
{Issue}: 6
{Year}: Jun 2018
暂无{DOI}: 10.1016/j.rec.2017.09.011
{Abstract}: <B>OBJECTIVE: </B>The cardio-ankle vascular index (CAVI) assesses arterial stiffness. We aimed to describe the distribution of CAVI in a Mediterranean population, to determine the proportion of CAVI ≥ 9 by sex and coronary risk level, and to assess the association of CAVI with classic cardiovascular risk factors and lifestyle patterns.<BR><B>METHODS: </B>This cross-sectional study was based on the population of Girona province. The CAVI was measured using the VaSera VS-1500.<BR><B>RESULTS: </B>Of 2613 individuals included in this study, the prevalence of CAVI ≥ 9 was 46.8% in men and 36.0% in women and significantly increased with coronary risk: from 21.1% and 24.8%, respectively to 76.7%, in the low-risk group, and 61.9% in the high-risk group. The CAVI increased with age in both sexes, being higher in men across all age groups. In men, CAVI ≥ 9 was associated with hypertension (OR, 2.70; 95%CI, 1.90-3.87) and diabetes (OR, 2.38; 95%CI, 1.52-3.78), body mass index (BMI) ≤ 25 to < 30 (OR, 0.44; 95%CI, 0.27-0.72) and BMI ≥ 30 (OR, 0.28; 95%CI, 0.14-0.58), and physical activity (OR, 0.66; 95%CI, 0.47-0.92). In women, CAVI ≥ 9 was associated with hypertension (OR, 2.22; 95%CI, 1.59-3.09), hypercholesterolemia (OR, 1.40; 95%CI, 1.01-1.94), and BMI ≥ 30 (OR, 0.38; 95%CI, 0.20-0.71).<BR><B>CONCLUSIONS: </B>The CAVI increases with age and is higher in men than in women. This index is associated with classic risk factors and coronary risk. It could be a good predictive biomarker, but further follow-up studies are required to assess its added value to cardiovascular risk stratification.