{Reference Type}: Case Reports
{Title}: Unusual axillary metastasis of recurrent nasopharyngeal cancer: A case report.
{Author}: Kuo DY;Chang MH;Wang SY;Hsieh PY;Shueng PW;
{Journal}: Medicine (Baltimore)
{Volume}: 96
{Issue}: 20
{Year}: May 2017
{Factor}: 1.817
{DOI}: 10.1097/MD.0000000000006854
{Abstract}: <B>BACKGROUND: </B>Nasopharyngeal carcinoma (NPC) has a high propensity of metastasis. The most commonly described sites of distant metastasis are the bones, lungs, and liver, whereas axillary metastasis is seldom reported.<BR><B>UNASSIGNED: </B>We hereby present the case of a 66-year-old man with NPC, cT2N2M0, at diagnosis. He had completed chemoradiotherapy and been disease-free for 7 years.<BR><B>UNASSIGNED: </B>After that period, late recurrence in the form of a solitary axillary lymph node metastasis was detected and confirmed by core-needle biopsy.<BR><B>METHODS: </B>The lesion was chemoresistant but responded to salvage radiotherapy at a dose of 65 Gy in 21 fractions.<BR><B>RESULTS: </B>Post-radiotherapy positron emission tomography scan showed no evidence of disease.<BR><B>CONCLUSIONS: </B>We suggested that long-term follow-up of NPC patients is important because a late relapse may occur at an unusual site. Aggressive management of solitary metastasis may achieve good outcome.