{Reference Type}: Case Reports
{Title}: Toxic epidermal necrolysis in a child 6 months post-hematopoietic stem cell transplantation.
{Author}: Oba U;Yamada H;Suenobu SI;Nakamura Y;Ito A;Hatano Y;Itonaga N;Ohshima K;Koga Y;Ohga S;Ihara K;
{Journal}: Pediatr Transplant
{Volume}: 21
{Issue}: 5
{Year}: Aug 2017
{Factor}: 1.551
{DOI}: 10.1111/petr.12931
{Abstract}: TEN is a rare and critical disease mostly caused by drugs. It is mediated by activated CD8+ T cells that cause keratinocyte apoptosis with the assistance of cytokines/chemokines. We herein report a pediatric case of TEN after allogeneic HSCT with precursor B-cell acute lymphoblastic leukemia (pre-B-ALL) in second complete remission. Although we did not evaluate the T-cell subpopulation in blood or skin lesion of the patient, an imbalanced immune reconstitution after HSCT might additively contribute to the development of TEN.