{Reference Type}: Journal Article
{Title}: Adherence to nutrition-based cancer prevention guidelines and breast, prostate and colorectal cancer risk in the MCC-Spain case-control study.
{Author}: Romaguera D;Gracia-Lavedan E;Molinuevo A;de Batlle J;Mendez M;Moreno V;Vidal C;Castelló A;Pérez-Gómez B;Martín V;Molina AJ;Dávila-Batista V;Dierssen-Sotos T;Gómez-Acebo I;Llorca J;Guevara M;Castilla J;Urtiaga C;Llorens-Ivorra C;Fernández-Tardón G;Tardón A;Lorca JA;Marcos-Gragera R;Huerta JM;Olmedo-Requena R;Jimenez-Moleon JJ;Altzibar J;de Sanjosé S;Pollán M;Aragonés N;Castaño-Vinyals G;Kogevinas M;Amiano P;
{Journal}: Int J Cancer
{Volume}: 141
{Issue}: 1
{Year}: 07 2017 1
{Factor}: 7.316
{DOI}: 10.1002/ijc.30722
{Abstract}: Prostate, breast and colorectal cancer are the most common tumours in Spain. The aim of the present study was to evaluate the association between adherence to nutrition-based guidelines for cancer prevention and prostate, breast and colorectal cancer, in the MCC-Spain case-control study. A total of 1,718 colorectal, 1,343 breast and 864 prostate cancer cases and 3,431 population-based controls recruited between 2007 and 2012, were included in the present study. The World Cancer Research Fund/American Institute for Cancer Research (WCRC/AICR) score based on six recommendations for cancer prevention (on body fatness, physical activity, foods and drinks that promote weight gain, plant foods, animal foods and alcoholic drinks; score range 0-6) was constructed. We used unconditional logistic regression analysis adjusting for potential confounders. One-point increment in the WCRF/AICR score was associated with 25% (95% CI 19-30%) lower risk of colorectal, and 15% (95% CI 7-22%) lower risk of breast cancer; no association with prostate cancer was detected, except for cases with a Gleason score ≥7 (poorly differentiated/undifferentiated tumours) (OR 0.87, 95% CI 0.76-0.99). These results add to the wealth of evidence indicating that a great proportion of common cancer cases could be avoided by adopting healthy lifestyle habits.