{Reference Type}: Case Reports
{Title}: Peroral endoscopic myotomy for treatment of Guillain-Barre syndrome-associated achalasia: A rare case.
{Author}: Shin SK;Kim KO;Kim EJ;Kim SY;Kim JH;Kim YJ;Chung JW;Kwon KA;Park DK;
{Journal}: World J Gastroenterol
{Volume}: 23
{Issue}: 5
{Year}: Feb 2017 7
{Factor}: 5.374
{DOI}: 10.3748/wjg.v23.i5.926
{Abstract}: Guillain-Barre syndrome (GBS)-associated achalasia is a very rare disease of uncertain cause. We report the case of a patient diagnosed with GBS-associated type I achalasia who was successfully treated with peroral endoscopic myotomy (POEM). A 30-year-old man who was diagnosed with GBS 3 mo before was referred to our department with dysphagia and meal-related regurgitation. The results of esophagography, endoscopy, and high-resolution manometry (HRM) revealed type I achalasia. POEM that utilized a submucosal tunneling technique was performed to treat the GBS-associated type I achalasia. After POEM, smooth passage of a contrast agent into the stomach was shown in follow-up esophagography, and follow-up HRM revealed a decrease in the mean integrated relaxation pressure 22.9 mmHg to 9.6 mmHg. The patient remained without dysphagia for 7 mo, even though the patient's neurological problems were not fully resolved. POEM may be a safe and effective treatment for GBS-associated type I achalasia.