{Reference Type}: Journal Article {Title}: Targeted tumor detection: guidelines for developing biotinylated diagnostics. {Author}: Jang JH;Kim WR;Sharma A;Cho SH;James TD;Kang C;Kim JS; {Journal}: Chem Commun (Camb) {Volume}: 53 {Issue}: 13 {Year}: Feb 2017 9 {Factor}: 6.065 {DOI}: 10.1039/c7cc00311k {Abstract}: The challenge in achieving precision medicine relies on how to advance and/or enhance new as well as old therapeutic strategies. Here, we highlight the significant role hydrophilicity of biotinylated fluorescent probe's plays on their cellular uptake behaviour.