{Reference Type}: Journal Article
{Title}: Endophthalmitis after intravitreal injections. Incidence, management and prognosis.
{Author}: Tarragó R;Olea JL;Ramírez C;Escudero L;
{Journal}: Arch Soc Esp Oftalmol
{Volume}: 92
{Issue}: 3
{Year}: Mar 2017
暂无{DOI}: 10.1016/j.oftal.2016.09.006
{Abstract}: <B>OBJECTIVE: </B>To assess the rate of endophthalmitis after intravitreal injection (IVI) in a «clean room» of a single health centre, following the guidelines of the Spanish Vitreo-Retinal Society (SERV). An analysis was performed on the culture specimens, response to treatment, and final outcomes (guidelines).<BR><B>METHODS: </B>A retrospective, observational study was conducted on a consecutive case series of patients diagnosed with infectious endophthalmitis after IVI in a single health centre between 2010 and 2015. Intravitreal and systemic treatment was given following the SERV guidelines. The patients were followed up the case was resolved.<BR><B>RESULTS: </B>There were 5 cases of endophthalmitis out of 9467 IVI (incidence 0.053%). Positive cultures were obtained in aqueous and/or vitreous fluid in all cases, with Staphylococcus epidermidis being involved in 4 out of 5 cases. In 2 cases, final visual acuity was non-light perception due to intractable retinal detachments after resolution of the infectious process.<BR><B>CONCLUSIONS: </B>IVI performed in a «clean room» have a low incidence of endophthalmitis. The most common infectious agent was Staphylococcus species. In 2 cases the functional prognosis was poor.