{Reference Type}: Journal Article {Title}: Surgical Management of Primary Scrotal Cancer. {Author}: Huang JH;Broggi M;Osunkoya AO;Master VA; {Journal}: Urol Clin North Am {Volume}: 43 {Issue}: 4 {Year}: Nov 2016 {Factor}: 2.766 {DOI}: 10.1016/j.ucl.2016.06.014 {Abstract}: Primary scrotal cancer is a rare urologic malignancy with various histologic subtypes. Management and outcomes are not designed optimally. Surgical excision is the recommended treatment for localized scrotal cancer, with assessment of the margins for disease. Closure of the defect can be performed with primary closure, skin grafts, flaps, or by secondary intention. Analysis of outcomes suggests that high-risk scrotal cancer may have a worse prognosis compared with penile cancer, and low-risk scrotal cancer may have a comparable prognosis. Understanding techniques for management and survival outcomes can help the urologist determine the appropriate course of treatment and improve patient care.