{Reference Type}: Case Reports
{Title}: An unusual case of spontaneous Mycobacterium chelonae corneal ulcer in a healthy middle-aged adult.
{Author}: Bhandari V;Sriganesh R;Relekar K;
{Journal}: Int Med Case Rep J
{Volume}: 9
{Issue}: 0
{Year}: 2016
暂无{DOI}: 10.2147/IMCRJ.S91518
{Abstract}: <B>BACKGROUND: </B>To report a rare presentation of culture-positive Mycobacterium chelonae corneal ulcer and its management.<BR><B>RESULTS: </B>We report a rare case of a patient with a history of chronic pain and blurriness of vision. Examination revealed a chronic nonhealing paracentral corneal ulcer inferiorly at the 5-7 o'clock meridian with anterior chamber reaction unresponsive to routine antibiotic and antifungal medications with Mantoux test positivity in a middle-aged nondiabetic patient with no prior history of trauma, ocular surgery, and contact lens usage. Ziehl-Neelsen staining of the nonhealing ulcer revealed acid-fast bacilli typical of M. chelonae, with subsequent culture positivity in Löwenstein-Jensen medium. Subsequent treatment with topical fortified amikacin and tobramycin resulted in rapid healing of the corneal ulcer.<BR><B>CONCLUSIONS: </B>M. chelonae presenting as a chronic nonhealing corneal ulcer spontaneously occurring in a healthy adult with no predisposing factor draws attention towards the need to have a good index of suspicion by performing a Ziehl-Neelsen stain and culture, and subsequent successful management with topical fortified amikacin and tobramycin.