{Reference Type}: Journal Article
{Title}: Study of Transposable Elements and Their Genomic Impact.
{Author}: Muñoz-Lopez M;Vilar-Astasio R;Tristan-Ramos P;Lopez-Ruiz C;Garcia-Pérez JL;
{Journal}: Methods Mol Biol
{Volume}: 1400
{Issue}: 0
{Year}: 2016
暂无{DOI}: 10.1007/978-1-4939-3372-3_1
{Abstract}: Transposable elements (TEs) have been considered traditionally as junk DNA, i.e., DNA sequences that despite representing a high proportion of genomes had no evident cellular functions. However, over the last decades, it has become undeniable that not only TE-derived DNA sequences have (and had) a fundamental role during genome evolution, but also TEs have important implications in the origin and evolution of many genomic disorders. This concise review provides a brief overview of the different types of TEs that can be found in genomes, as well as a list of techniques and methods used to study their impact and mobilization. Some of these techniques will be covered in detail in this Method Book.