{Reference Type}: Case Reports
{Title}: Unusual case of drug-induced cholestasis due to glucosamine and chondroitin sulfate.
{Author}: Ip S;Jeong R;Schaeffer DF;Yoshida EM;
{Journal}: World J Hepatol
{Volume}: 7
{Issue}: 24
{Year}: Oct 2015 28
暂无{DOI}: 10.4254/wjh.v7.i24.2559
{Abstract}: Glucosamine (GS) and chondroitin sulfate (CS) are common over-the-counter (OTC) supplements used in the treatment of osteoarthritis. These medications are seemingly safe, but there are increasing reports of hepatotoxicity with these supplements. We reported a unique case of drug-induced cholestasis caused by GS and CS in a combination tablet. The etiology of the jaundice was overlooked despite extensive investigations over a three-month period. Unlike drug-induced hepatocellular injury, drug-induced cholestatic jaundice with GS and CS has only been reported twice before. This case emphasizes the importance of a complete medication history, especially OTC supplements, in the assessment of cholestasis.