{Reference Type}: Journal Article
{Title}: [How to explore breast skin lesion?: Guidelines].
{Author}: Boulanger L;Demetz J;
{Journal}: J Gynecol Obstet Biol Reprod (Paris)
{Volume}: 44
{Issue}: 10
{Year}: Dec 2015
暂无{DOI}: 10.1016/j.jgyn.2015.09.040
{Abstract}: A change in the shape or appearance of the nipple-areola complex, especially if it is unilateral and recent appearance, is a sign of underlying breast tumor. Breast imaging is then required (grade C). Any erythematous lesion of the nipple or nipple-areola can be a Paget's disease, an adenoma of the nipple or a nipple eczema. Clinical course and pattern can point to a diagnosis without sufficient specificity (LE4). If nipple eczema is suspected, it is recommended to perform a test treatment with topical corticosteroids. In case of failure or if a Paget's disease of the breast is suspected, a biopsy must be done. When indicated, it is not possible to recommend a biopsy modality (scrape cytology, punch biopsy, nipple core biopsy and surgical excision) compared to another. When imaging exploration of the nipple-areola complex is necessary, ultrasound and mammography are recommended as first-line. In the absence of signal, an MRI is recommended as second-line (grade C).