{Reference Type}: Journal Article {Title}: The Riddle of Nonalcoholic Fatty Liver Disease: Progression From Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis. {Author}: Sharma M;Mitnala S;Vishnubhotla RK;Mukherjee R;Reddy DN;Rao PN; {Journal}: J Clin Exp Hepatol {Volume}: 5 {Issue}: 2 {Year}: Jun 2015 暂无{DOI}: 10.1016/j.jceh.2015.02.002 {Abstract}: Nonalcoholic fatty liver (NAFL) is an emerging global epidemic which progresses to nonalcoholic steatohepatitis (NASH) and cirrhosis in a subset of subjects. Various reviews have focused on the etiology, epidemiology, pathogenesis and treatment of NAFLD. This review highlights specifically the triggers implicated in disease progression from NAFL to NASH. The integrating role of genes, dietary factors, innate immunity, cytokines and gut microbiome have been discussed.