{Reference Type}: Case Reports
{Title}: Primary testicular Ph-positive B lymphoblastic lymphoma: an unusual presentation and review.
{Author}: Zhu J;Zhang S;Zhu L;Li X;Wang Y;Duan Y;Huang W;
{Journal}: Cancer Biol Ther
{Volume}: 16
{Issue}: 8
{Year}: 2015
{Factor}: 4.875
{DOI}: 10.1080/15384047.2015.1056412
{Abstract}: Primary testicular B-lymphoblastic lymphoma is a rare entity. Primary testicular Ph-positive B lymphoblastic lymphoma was not reported before. We reported a 27-year-old man with primary testicular Ph-positive B lymphoblastic lymphoma, for which fluorescent in-situ hybridization (FISH) for the Philadelphia chromosome was not performed at the initial hospitalization. The patient showed manifestation of Ph-positive acute lymphoblastic leukemia at relapse. In this report, we reviewed the current literature about primary testicular B-lymphoblastic lymphoma, Ph-positive lymphoma and Ph-positive clone evolution. This report has 3 meanings. First: This is first report on primary testicular Ph-positive B lymphoblastic lymphoma. Second: This shows the importance of cytogenics for lymphoma treatment. Third: This implies Philadelphia-positive subclone evolution.