{Reference Type}: Journal Article
{Title}: Anti-inflammation furanoditerpenoids from Caesalpinia minax Hance.
{Author}: Dong R;Yuan J;Wu S;Huang J;Xu X;Wu Z;Gao H;
{Journal}: Phytochemistry
{Volume}: 117
{Issue}: 0
{Year}: Sep 2015
{Factor}: 4.004
{DOI}: 10.1016/j.phytochem.2015.06.025
{Abstract}: Cassane skeletons are rare in nature, but often possess valuable medicinal properties. A furanoditerpenoid with an unusual A-seco-rearranged cassane skeleton, neocaesalminin A, and five furanoditerpenoids were isolated from seeds of Caesalpinia minax Hance, along with six known cassane derivatives, 7-O-acetyl-bonducellpin C, caesalmin F, caesalmin C, ζ-caesalmin, caesalmin E1 and caesalpinin K. Compound structures were determined by spectroscopy (HR-ESI-MS, UV, IR, 1D NMR, 2D NMR), X-ray crystallography and quantum chemical computation of electronic circular dichroism). Three of the previously known compounds exhibited significant inhibition of nitric oxide production of RAW264.7 macrophages stimulated by lipopolysaccharide (LPS).