{Reference Type}: Journal Article {Title}: Adult hepatic cavernous hemangioma with highly elevated α-fetoprotein: A case report and review of the literature. {Author}: Wang HY;Zhang L;Wu J;Zhang ZJ;Peng BG;Liang LJ;Zhou Q; {Journal}: Oncol Lett {Volume}: 9 {Issue}: 2 {Year}: Feb 2015 {Factor}: 3.111 {DOI}: 10.3892/ol.2014.2769 {Abstract}: A 47-year-old male presented with a six-month history of fatigue and a four-month history of alanine and aspartate aminopherase elevation. Laboratory examination revealed that the serum α-fetoprotein (AFP) level was 371.51 μg/l (normal range, 0-20 μg/l), and a computed tomography scan revealed a hypodense lesion in the left hepatic lobe. During laparotomy, a dark red-colored soft tumor (1.5×1.7 cm in diameter) was found in segment eight of the liver. Intra-operative pathology and post-operative histopathology examinations revealed that the tumor was a hepatic cavernous hemangioma. The serum AFP level was decreased to 24.45 μg/l by the second post-operative week. The literature was searched and only three similar cases were found. A brief review of this rare disease entity was produced, which attempted to explain this appearance reasonably.