{Reference Type}: English Abstract
{Title}: [Clinical characteristics of nail lichen planus and follow-up: a descriptive study of 20 patients].
{Author}: Chiheb S;Haim H;Ouakkadi A;Benchikhi H;
{Journal}: Ann Dermatol Venereol
{Volume}: 142
{Issue}: 1
{Year}: Jan 2015
{Factor}: 0.934
{DOI}: 10.1016/j.annder.2014.09.023
{Abstract}: <B>BACKGROUND: </B>Nail lichen planus (NLP) occurs in 10% of patients with disseminated disease but it can also occur in isolation. The outcome of treatment is usually disappointing and data about its long-term prognosis are lacking.<BR><B>OBJECTIVE: </B>To study clinical features, response to treatment and follow-up of a series of 20 patients with NLP.<BR><B>METHODS: </B>A descriptive study was conducted of 20 patients with histologically confirmed NLP seen at consultations for nail disorders between September 2009 and April 2013.<BR><B>RESULTS: </B>The mean age was 35 years (9-56 years) with no gender preponderance. Forty percent of patients were children. Stress was an evident triggering factor in 20% of patients. The mean duration was around 48 months (2 months to 10 years). Only 25% of patients had extra-ungual lesions. All 20 nails were affected in 55% of patients. Nail matrix involvement was observed in 85% of cases and 55% had nail-bed involvement. Twenty-five percent of patients were presenting severe involvement such as pterygium or anonychia. Intramuscular corticosteroids were given to 10 patients. In 80% of patients, the NLP was limited or regressed rapidly from the third injection. The average follow-up was 24 months.<BR><B>CONCLUSIONS: </B>Our study highlights the frequency of paediatric forms and of often aesthetically unacceptable nail scarring. Early diagnosis of NLP, notably in children, would allow initiation of adequate treatment that could perhaps limit the risk of such sequelae.