{Reference Type}: Case Reports
{Title}: Congenital leukemia.
{Author}: Raj A;Talukdar S;Das S;Gogoi PK;Das D;Bhattacharya J;
{Journal}: Indian J Hematol Blood Transfus
{Volume}: 30
{Issue}: 0
{Year}: Sep 2014
{Factor}: 0.915
{DOI}: 10.1007/s12288-013-0307-7
{Abstract}: Congenital leukemia is a rare but a well-documented disease in which leukemic process is detected at birth or very shortly thereafter (Philip McCoy and Roy Overton, Commun Clin Cytom 22:85-88, 1995). These leukemias represent approximately 0.8 % of all childhood leukemias. We present a case of congenital acute myeloid leukemia manifesting from the very first day of birth. Diagnosis of acute myeloid leukemia was suspected by the presence of blasts in the peripheral blood smear and was confirmed on bone marrow by flowcytometry. Karyotyping revealed Trisomy 21.