{Reference Type}: Consensus Development Conference
{Title}: Identifying and addressing unmet clinical needs in Ph-neg classical myeloproliferative neoplasms: a consensus-based SIE, SIES, GITMO position paper.
{Author}: Barosi G;Vannucchi AM;De Stefano V;Pane F;Passamonti F;Rambaldi A;Saglio G;Barbui T;Tura S;
{Journal}: Leuk Res
{Volume}: 38
{Issue}: 2
{Year}: Feb 2014
{Factor}: 3.715
{DOI}: 10.1016/j.leukres.2013.09.008
{Abstract}: This article presents the results of group discussion among experts from SIE, SIES and GITMO societies aimed at highlighting unmet challenges in the management of Ph-neg myeloproliferative neoplasms (MPNs). The issues analyzed were: diagnosis of prefibrotic myelofibrosis; diagnosis of Ph-neg MPNs in the setting of splanchnic vein thrombosis (SVT); management of low-risk PV and low-risk ET patients with JAK2V617F mutation; molecular biomarkers in the prognostic evaluation of myelofibrosis (MF); ruxolitinib therapy in low-risk MF; therapy in patients with SVT-associated Ph-neg MPN; indications of splenectomy in MF. For each of these issues, proposals for advancement in clinical research were addressed.