{Reference Type}: Journal Article
{Title}: Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme.
{Author}: Sander A;Wosniok W;Gabel D;
{Journal}: Appl Radiat Isot
{Volume}: 88
{Issue}: 0
{Year}: Jun 2014
{Factor}: 1.787
{DOI}: 10.1016/j.apradiso.2013.11.092
{Abstract}: Boron neutron capture therapy (BNCT) with Na2B12H11SH (BSH) or p-dihydroxyborylphenylalanine (BPA), and with a combination of both, was compared to radiotherapy with temozolomide, and the number of patients required to show statistically significant differences between the treatments was calculated. Whereas arms using BPA require excessive number of patients in each arm, a two-armed clinical trial with BSH and radiotherapy plus temozolomide is feasible.