{Reference Type}: Case Reports
{Title}: Primary cardiac synovial sarcoma: a case report and literature review.
{Author}: Yokouchi Y;Hiruta N;Oharaseki T;Ihara F;Oda Y;Ito S;Yamashita H;Ozaki S;Gomi T;Takahashi K;
{Journal}: Pathol Int
{Volume}: 61
{Issue}: 3
{Year}: Mar 2011
{Factor}: 2.121
{DOI}: 10.1111/j.1440-1827.2010.02631.x
{Abstract}: Primary cardiac synovial sarcoma is a rare disease. A 51-year-old man visited our hospital with the chief complaint of palpitations and shortness of breath while exercising. Copious bloody pericardial effusion and a multicystic intrapericardial tumor were detected. A primary cardiac malignant tumor was suspected, an open-chest tumor resection was performed with the objectives of diagnosis and treatment. Histologically, the tumor cells were uniformly spindle-shaped with an ovoid or oval nucleus, they had proliferated in fascicular fashion. In addition myxoid degeneration, a hemangiopericytomatous vascular pattern and pseudorosette formation were seen in some areas of the tumor. Based on the histopathological and immunohistochemical findings and reverse transcription polymerase chain reaction detection of SS18-SSX1 fusion transcripts, a monophasic fibrous type synovial sarcoma was diagnosed. Postoperative radiation therapy was administered and there had been no recurrence 9 months after the surgery.