{Reference Type}: Journal Article
{Title}: In vivo inhibition of TonB-dependent processes by a TonB box consensus pentapeptide.
{Author}: Tuckman M;Osburne MS;
{Journal}: J Bacteriol
{Volume}: 174
{Issue}: 1
{Year}: Jan 1992
{Factor}: 3.476
{DOI}: 10.1128/jb.174.1.320-323.1992
{Abstract}: The TonB box, a conserved pentapeptide sequence found in TonB-dependent colicins and receptors, is thought to interact physically with the TonB protein to facilitate TonB-dependent processes. Strains of Escherichia coli were treated in vivo with the synthetic TonB box pentapeptide Glu-Thr-Val-Ile-Val. The pentapeptide inhibited several TonB-dependent processes, including cell growth in low-iron medium, phi 80 infection, and killing by colicins B and Ia. Two unrelated control pentapeptides had no effect on TonB-dependent processes.