%0 Journal Article
%T Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis.
%A Eijkemans M
%A Mommers M
%A Harskamp-van Ginkel MW
%A Vrijkotte TGM
%A Ludvigsson J
%A Faresjö Å
%A Bergström A
%A Ekström S
%A Grote V
%A Koletzko B
%A Bønnelykke K
%A Eliasen AU
%A Bager P
%A Melbye M
%A Annesi-Maesano I
%A Baïz N
%A Barros H
%A Santos AC
%A Duijts L
%A Mensink-Bout SM
%A Flexeder C
%A Koletzko S
%A Schikowski T
%A Eggesbø MÅ
%A Lenters V
%A Fernández-Tardón G
%A Subiza-Perez M
%A Garcia-Aymerich J
%A López-Vicente M
%A Sunyer J
%A Torrent M
%A Ballester F
%A Kelleher C
%A Mehegan J
%A Berg AV
%A Herberth G
%A Standl M
%A Kuehni CE
%A Pedersen ESL
%A Jansen M
%A Gehring U
%A Boer JMA
%A Devereux G
%A Turner S
%A Peltola V
%A Lagström H
%A Inskip HM
%A Pike KC
%A Dalmeijer GW
%A Ent CKV
%A Thijs C
%J BMJ Open Respir Res
%V 11
%N 1
%D 2024 Aug 15
%M 39147399
%F 5.054
%R 10.1136/bmjresp-2023-001630
%X <B>OBJECTIVE: </B>To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.<BR><B>METHODS: </B>Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.<BR><B>METHODS: </B>Children aged 0-18 years from 26 European birth cohorts.<BR><B>METHODS: </B>136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood.<BR><B>METHODS: </B>Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6-18 years.<BR><B>RESULTS: </B>Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results.<BR><B>CONCLUSIONS: </B>Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.