%0 Journal Article
%T Pulmonary Function, Functional Capacity, Respiratory, and Locomotor Muscle Strength after Severe to Critically Ill COVID-19: A Long-Term Study.
%A Ngamsutham T
%A Chaiwong W
%A Dacha S
%A Sitlertpisan P
%A Pothirat C
%A Duangjit P
%A Deesomchok A
%A Liwsrisakun C
%A Bumroongkit C
%A Theerakittikul T
%A Limsukon A
%A Trongtrakul K
%A Niyatiwatchanchai N
%A Tajarernmuang P
%J Tuberc Respir Dis (Seoul)
%V 0
%N 0
%D 2024 08 14
%M 39139078
暂无%R 10.4046/trd.2024.0044
%X The sequelae of post-coronavirus disease 2019 (COVID-19) pneumonia on lung function, exercise capacity, and quality of life were observed in both short-term and long-term. However, the study about the respiratory and locomotor muscle strength in severe and critically ill COVID-19 survivors are still limited. Therefore, we aimed to examine long-term pulmonary function, functional capacities, and respiratory and locomotor body muscle strength in severe to critically ill post-COVID-19 survivors.<BR>A prospective observational study was conducted in twenty-two post-COVID-19 pneumonia and healthy adults. Clinical characteristics during admission, pulmonary function, functional capacity, respiratory muscles, and locomotor muscles strength were examined at 1, 3, and 6 months after discharge from the hospital.<BR>The generalized linear mixed model showed that percent predicted of forced expiratory volume in the first second (%FEV1), percent predicted of forced vital capacity (%FVC), maximum inspiratory pressure (MIP), handgrip strength, six-minute walk distance (6-MWD), and 5-times sit to stand (5TSTS) were significantly lower in post-COVID-19 pneumonia patients than in healthy subjects during the follow-up period. The percent predicted of maximal voluntary ventilation (%MVV), and locomotor muscle strength were not different between the two groups throughout the follow-up period. Among post-COVID-19 pneumonia patients, %FEV1, %FVC, %MVV, 5TSTS, locomotor muscle strength significantly improved at three months compared to baseline at one month.<BR>Pulmonary function, functional capacity, respiratory, and locomotor muscle strength of survivors from COVID-19 were impaired and recovery was observed after three to six months. These emphasized the need to evaluate the long-term consequences of COVID-19.