%0 Journal Article
%T Fluorescein Angiography Parameters in Premature Neonates.
%A da Cruz NFS
%A Hoyek S
%A Sengillo JD
%A Rodríguez A
%A de Oliveira G
%A Negron CI
%A Patel NA
%A Berrocal AM
%J Ophthalmol Sci
%V 4
%N 6
%D 2024 Nov-Dec
%M 39132023
暂无%R 10.1016/j.xops.2024.100561
%X <B>UNASSIGNED: </B>To describe fluorescein angiography (FA) parameters observed in premature neonates with retinopathy of prematurity (ROP).<BR><B>UNASSIGNED: </B>Retrospective case series.<BR><B>UNASSIGNED: </B>Patients with ROP who underwent FA imaging using Retcam at Holtz Children's Hospital from November 2014 to October 2022.<BR><B>UNASSIGNED: </B>Fluorescein angiography images of the included patients were analyzed with a focus on the timing of angiography phases, including choroidal flush, retinal, and recirculation phases. Gestational age, birth weight (BW), age at imaging, treatment choice, and any FA complications were documented.<BR><B>UNASSIGNED: </B>Dose of fluorescein administered, onset and duration of each angiography phase, and FA findings in ROP-treated patients.<BR><B>UNASSIGNED: </B>A total of 72 images of 72 eyes were reviewed. Image quality was deemed suitable for inclusion in 64 eyes (88.9%) of 43 patients. The mean gestational age and BW at birth were 24.4 ± 1.9 weeks and 607.8 ± 141.3 g, respectively. The mean postmenstrual age at FA imaging was 50.5 ± 40.8 weeks. All eyes (100%) received treatment with intravitreal injection of anti-VEGF at a mean age of 35.5 ± 2.4 weeks. The onset and duration of angiography phases were relatively variable within the cohort. Choroidal flush occurred at a mean time of 12.2 seconds (range: 6-22 seconds). A subsequent retinal phase was documented at a mean time of 11.96 seconds (range: 3-22 seconds). Recirculation phase was complete at an average time of 2.15 minutes (range: 1-5.45 minutes) postfluorescein injection. None of patients developed allergic reactions to fluorescein injection, such as rash, respiratory distress, tachycardia, fever, or local injection site reactions.<BR><B>UNASSIGNED: </B>Angiographic phases on FA in preterm infants with ROP are variable and may occur earlier than the established references for adults.<BR><B>UNASSIGNED: </B>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.