%0 Journal Article %T Nanosensors Based on Bimetallic Plasmonic Layer and Black Phosphorus: Application to Urine Glucose Detection. %A Houari F %A El Barghouti M %A Mir A %A Akjouj A %J Sensors (Basel) %V 24 %N 15 %D 2024 Aug 5 %M 39124105 %F 3.847 %R 10.3390/s24155058 %X This paper presents a new biosensor design based on the Kretschmann configuration, for the detection of analytes at different refractive indices. Our studied design consists of a TiO2/SiO2 bi-layer sandwiched between a BK7 prism and a bimetallic layer of Ag/Au plasmonic materials, covered by a layer of black phosphorus placed below the analyte-containing detection medium. The different layers of our structure and analyte detection were optimized using the angular interrogation method. High performance was achieved, with a sensitivity of 240 deg/RIU and a quality factor of 34.7 RIU-1. This biosensor can detect analytes with a wide refractive index range between 1.330 and 1.347, such as glucose detection in urine samples using a refractive index variation of 10-3. This capability offers a wide range of applications for biomedical and biochemical detection and selectivity.