%0 Case Reports
%T Critical illness-associated cerebral microbleeds involving the corpus callosum following cardiac arrest: A case report.
%A Srichawla BS
%A Fang T
%A Kipkorir V
%A Lalla R
%J Medicine (Baltimore)
%V 103
%N 32
%D 2024 Aug 9
%M 39121333
%F 1.817
%R 10.1097/MD.0000000000039273
%X BACKGROUND: Critical illness-associated cerebral microbleeds (CI-aCMBs) are emerging as significant radiographic findings in patients with hypoxic ischemic injuries. Their occurrence, particularly in the corpus callosum, warrants a closer examination due to the potential implications for neurological outcomes in critically ill patients. We aim to describe a rare case of CI-aCMBs within the corpus callosum following cardiac arrest with the goal of bolstering the scientific literature on this topic.
METHODS: A 34-year-old man with a history of polysubstance abuse was found unconscious and experienced a pulseless electrical activity (PEA) cardiac arrest after a suspected drug overdose. Post-resuscitation, the patient exhibited severe respiratory distress, acute kidney injury, and profound neurological deficits.
METHODS: Initial magnetic resonance imaging scans post-cardiac arrest showed no acute brain abnormalities. However, subsequent imaging revealed extensive cerebral microbleeds predominantly in the corpus callosum, diagnosed as CI-aCMBs. These findings were made in the absence of high signal intensity on T2-weighted images, suggesting a unique pathophysiological profile of microhemorrhages.
METHODS: The patient underwent targeted temperature management (TTM) and supportive care in the intensive care unit after cardiac arrest.
RESULTS: He was subsequently extubated and had significant recovery without any neurological deficits.
CONCLUSIONS: CI-aCMBs is a rare radiographic finding after cardiac arrest. These lesions may be confined to the corpus callosum and the long-term clinical and radiographic sequelae are still largely unknown.