%0 Journal Article
%T Evidence-based review on symptomatic management of Huntington's disease.
%A Shin JH
%A Yang HJ
%A Ahn JH
%A Jo S
%A Chung SJ
%A Lee JY
%A Kim HS
%A Kim M
%A  
%J J Mov Disord
%V 0
%N 0
%D 2024 Aug 9
%M 39117301
%F 4.229
%R 10.14802/jmd.24140
%X Huntington's disease (HD) is a neurodegenerative disorder with a significant impact on patients' quality of life, characterized by motor, behavioral, and cognitive impairments. This evidence-based review, conducted by the Korean Huntington Disease Society (KHDS) task force, systematically examines current pharmacological and non-pharmacological interventions for symptomatic management of HD. Following PRISMA guidelines, databases were searched for studies up to August 2022, focusing on 23 symptoms across four domains: motor, neuropsychological, cognition, and others. This review provides a comprehensive and systematic approach to the management of HD, highlighting the need for more high-quality clinical trials to develop robust evidence-based guidelines.