%0 Journal Article
%T Chiral bifunctional sulfide-catalyzed enantioselective bromolactonizations of α- and β-substituted 5-hexenoic acids.
%A Sumida S
%A Okuno K
%A Mori T
%A Furuya Y
%A Shirakawa S
%J Beilstein J Org Chem
%V 20
%N 0
%D 2024
%M 39109297
%F 2.544
%R 10.3762/bjoc.20.158
%X Enantioselective halolactonizations of sterically less hindered alkenoic acid substrates without substituents on the carbon-carbon double bond have remained a formidable challenge. To address this limitation, we report herein the asymmetric bromolactonization of 5-hexenoic acid derivatives catalyzed by a BINOL-derived chiral bifunctional sulfide.