%0 Case Reports
%T Long-term successfull management of recurrent episodes of nontuberculous mycobacterial infection in an apparently healthy Chinese woman.
%A Raccagni AR
%A Mori G
%A de Chaurand VP
%A Dell'Acqua R
%A Cirillo DM
%A Oltolini C
%A Mazzi B
%A Scomazzoni F
%A Castagna A
%A Guffanti M
%J Ann Clin Microbiol Antimicrob
%V 23
%N 1
%D 2024 Aug 3
%M 39097716
%F 6.781
%R 10.1186/s12941-024-00732-0
%X <B>BACKGROUND: </B>Disseminated non-tuberculous mycobacteria (dNTM) infections are mostly reported among individuals with an underlying congenital or acquired immunodeficiency or receiving immunosuppressive treatment, but are rarely documented in otherwise healthy subjects.<BR><B>METHODS: </B>We describe a case of recurrent disseminated mycobacterial infection in an apparently immunocompetent Chinese woman. Mycobacterium szulgai and Mycobacterium avium-complex were identified in distinct episodes. Long-term antimycobacterial therapy was administered given the occurrence of recurrent events when off-treatment. Successful management over more than 10 years and immunologic data are reported.<BR><B>CONCLUSIONS: </B>This case-report highlights that dNTM should be suspected also among apparently immunocompetent hosts and that thorough assessment of underling immune-impairments is helpful to define patients' management. Long-term antimycobacterial therapy and close monitoring is required to grant successful outcomes in case of recurrent dNTM infections.