%0 Journal Article
%T Superior vena cava isolation using a pentaspline pulsed-field ablation catheter: feasibility and safety in patients undergoing atrial fibrillation catheter ablation.
%A Ollitrault P
%A Chaumont C
%A Font J
%A Manninger M
%A Conti S
%A Matusik PT
%A Mulder BA
%A Ferchaud V
%A Pellissier A
%A Al Khoury M
%A Milliez P
%A Champ-Rigot L
%A Anselme F
%J Europace
%V 26
%N 7
%D 2024 Jul 2
%M 39082719
%F 5.486
%R 10.1093/europace/euae160
%X <B>OBJECTIVE: </B>Superior vena cava (SVC) isolation during atrial fibrillation catheter ablation is limited by the risk of collateral damage to the sinus node and/or the phrenic nerve. Due to its tissue-specificity, we hypothesized the feasibility and safety of pulsed-field ablation (PFA)-based SVC isolation.<BR><B>RESULTS: </B>One hundred and five consecutive patients undergoing PFA-based AF catheter ablation were prospectively included. After pulmonary vein isolation (±posterior wall isolation and electrical cardioversion), SVC isolation was performed using a standardized workflow. Acute SVC isolation was achieved in 105/105 (100%) patients after 6 ± 1 applications. Transient phrenic nerve stunning occurred in 67/105 (64%) patients but without phrenic nerve palsy at the end of the procedure and at hospital discharge. Transient high-degree sinus node dysfunction occurred in 5/105 (4.7%) patients, with no recurrence at the end of the procedure and until discharge. At the 3-month follow-up visit, no complication occurred.<BR><B>CONCLUSIONS: </B>SVC isolation using a pentaspline PFA catheter is feasible and safe.