%0 Journal Article %T Clinical Features of Children with COVID-19 in Initial Time of Pandemic. %A Hayashi T %A Murano Y %A Muto Y %A Takasu M %A Sato H %A Yagisawa H %A Oshima K %A Miyazaki N %A Adachi T %A Hisata K %A Nakazawa T %A Rahman M %A Gilmour S %A Shimizu T %J Juntendo Iji Zasshi %V 68 %N 6 %D 2022 %M 39081386 暂无%R 10.14789/jmj.JMJ22-0005-OA %X UNASSIGNED: COVID-19 (Coronavirus Disease 2019) is now a global pandemic. Although children are said to have mild symptom, their clinical features are not known well. We conducted a retrospective study during initial term of pandemic to understand the difference of clinical features including clinical symptoms and patients' characteristics of COVID-19 children and those without COVID-19.
UNASSIGNED: To compare clinical features between children with and without COVID-19, we collected data on children who received a COVID-19 test between March 25th and October 31st, 2020. All data were collected from medical records.
UNASSIGNED: There were three groups of patients in the study sample; patients with COVID-19, patients with close COVID-19 contact and performed COVID-19 tests, and patients suspected COVID-19 but tested negative. We analyzed the clinical features of the groups.
UNASSIGNED: A total of 108 patients were included in this study, of whom 30 were patients with COVID-19, 25 were patients with close COVID-19 contact, 51 were suspected COVID-19 but tested negative, and two were excluded because they were infants born from COVID-19 mothers. The statistical analysis showed that children with COVID-19 had contact with COVID-19 patients had fewer clinical symptoms including cough and fever compared to children with a negative test of COVID-19. Sensitivity analysis showed that fever, cough, fever and/or cough could not distinguish children with COVID-19 from those without COVID-19. As conclusion, children with COVID-19 have less symptoms as fever or cough and the clinical symptoms cannot distinguish them from children with other diseases.