%0 Journal Article
%T Potential role of the methanolic extract for Olea europaea (stem and leaves) on sporulation of Eimeria papillata oocysts: In vitro study.
%A Al-Shaebi EM
%A Al-Quraishy S
%A Abdel-Gaber R
%J Biomed Chromatogr
%V 0
%N 0
%D 2024 Jul 30
%M 39079944
%F 1.911
%R 10.1002/bmc.5972
%X Many plants are efficient anticoccidial agents owing to their content of active chemicals. Drug-resistant Eimeria species have emerged as a result of excessive drug use. The current work aimed to investigate the oocysticidal activity (Eimeria papillata) of Olea europaea stem extract (OESE) and leaf extract (OELE) in vitro. The results of gas chromatography-mass spectrometry analysis for OELE and OESE showed the presence of 12 and 9 phytochemical compounds, respectively. Also, chemical examination revealed that the plant extracts are rich in phenols, flavonoids and tannins. Additionally, the best radical scavenging activity of OESE and OELE was at a concentration of 100 μg/ml, reaching 92.04 ± 0.02 and 92.4 ± 0.2%, respectively. The in vitro study revealed that concentrations of 200 mg/ml from OESE and OELE caused significant inhibition (100%) of process sporulation for E. papillata oocysts, in contrast to the other commercial products, which displayed varying degrees of suppression sporulation. Our findings showed that OESE and OELE have anticoccidial activity, which motivates further the conduction of in vivo studies in the search for a less expensive and more efficient cure.