%0 Journal Article
%T EVolution in ALS diagnosis: molecular markers in extracellular vesicles.
%A Codron P
%A Millecamps S
%A Corcia P
%J Trends Mol Med
%V 0
%N 0
%D 2024 Jul 27
%M 39069396
%F 15.272
%R 10.1016/j.molmed.2024.07.006
%X The identification of biomarkers for amyotrophic lateral sclerosis (ALS) is a central issue in disease research. In a recent article, Chatterjee et al. show that blood extracellular vesicles (EVs) with high levels of transactive response DNA-binding protein 43 (TDP-43) accurately discriminate patients with ALS from controls and correlate with disease severity, providing a promising biomarker for early diagnosis and monitoring.