%0 Journal Article
%T Combined perceptual and chemical analyses show no compelling evidence for ovulatory cycle shifts in women's axillary odour.
%A Zetzsche M
%A Weiß BM
%A Kücklich M
%A Stern J
%A Birkemeyer C
%A Widdig A
%A Penke L
%J Proc Biol Sci
%V 291
%N 2027
%D 2024 Aug
%M 39043247
%F 5.53
%R 10.1098/rspb.2023.2712
%X Although men's attraction to women's body odour has been suggested to vary over the ovulatory cycle, peaking around the fertile window, we still lack methodologically robust evidence corroborating this effect. Further, the chemical underpinnings of male preference for the odour of ovulating women remain unknown. Here, we combined perceptual and chemical analyses to investigate the axillary odour of naturally cycling women over 10 days, covering the gradual change in fertility across the ovulatory cycle with a focus on fertile days. The fertile state was confirmed by urinary ovulation tests as well as salivary oestradiol and progesterone levels. Men rated the scent of unfamiliar women, resembling a first encounter. We used multivariate analyses to relate variation in both odour ratings and chemical composition to female conception probability, temporal distance to ovulation and ovarian hormone levels. Our results provide no evidence that males prefer the odour of fertile women. Furthermore, the volatile analysis indicated no link between axillary odour composition and current fertility status. Together, our results showed no convincing support for a chemical fertility cue in women's axillary odour, questioning the presence of olfactory fertility information that is recognizable during first encounters in modern humans.