%0 Journal Article
%T Skeletal indicators of pathology in the context of early tooth loss in children: A systematic literature review.
%A Ribeiro A
%A Decaup PH
%A Andriantavy M
%A Couture C
%A Garot E
%J Int J Paleopathol
%V 46
%N 0
%D 2024 Sep 18
%M 39029336
%F 1.448
%R 10.1016/j.ijpp.2024.07.001
%X <B>OBJECTIVE: </B>To provide an evidence-based resource for paleopathologists to consider multiple skeletal indicators of pathology associated with early tooth loss in children to aid in diagnosis.<BR><B>METHODS: </B>Three databases (Cochrane Library, MedLine, and Scopus) were used for a review.<BR><B>METHODS: </B>According to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) criteria, a systematic review guideline, 85 articles were selected.<BR><B>RESULTS: </B>A total of 189 children had a syndrome or disease associated with early tooth loss. Our review, based on 25 diseases, lists the bone and dental lesions observable in archeological remains.<BR><B>CONCLUSIONS: </B>Based on a review of the literature, a synthesis of 25 diseases and syndromes that may be associated with premature loss of permanent or deciduous teeth in children was developed for paleopathologists. It highlights the importance of a thorough dental examination by paleopathologists to further assess past health conditions.<BR><B>CONCLUSIONS: </B>This paper provides an extensive resource addressing early tooth loss in childhood to assist researchers with differential diagnosis.<BR><B>CONCLUSIONS: </B>The articles included in this review are case reports based on living populations.<BR><B>UNASSIGNED: </B>Further studies into diseases and their association with early tooth loss would complement this work, as would utilizing the differential diagnoses on archeological individuals to clarify its value and limitations.