%0 Case Reports %T Uterine Fibroid-Associated Massive Pulmonary Embolism: A Report of Two Cases. %A Brown D %A Ghalib N %A Wu J %A Shahzadi A %A Simpson T %A Sharma A %A Bejugam VR %A Soodhan K %A Thachil R %J Cureus %V 16 %N 6 %D 2024 Jun %M 39011196 暂无%R 10.7759/cureus.62436 %X This report details cases of uterine fibroid-associated deep vein thrombosis leading to massive pulmonary embolism, as well as the likely associated physiology. Two women, aged 33 and 37, presented with fibroid-associated pulmonary embolism. They both had large uterine sizes and no underlying thrombophilia. Case 1 had an uncomplicated course, whereas Case 2 had a course complicated by cardiac arrest and prolonged recovery. The presence of fibroids enhances coagulation and platelet adhesion. Mechanical compression also plays a role in predisposing to thrombosis. There may be a role for preoperative screening, especially in those with an elevated estimated uterine weight.