%0 Journal Article
%T STOP-Bang questionnaire in patients hospitalized with acute symptomatic pulmonary embolism.
%A Briceño W
%A Barbero E
%A Mañas E
%A González S
%A García-Ortega A
%A Oscullo G
%A García-Sánchez A
%A Cano-Pumarega I
%A Martinez-Garcia MÁ
%A Jimenez D
%J Sleep
%V 0
%N 0
%D 2024 Jul 12
%M 38995206
%F 6.313
%R 10.1093/sleep/zsae158
%X <B>OBJECTIVE: </B>The STOP-Bang questionnaire is a validated screening tool for obstructive sleep apnea (OSA). We conducted this study to validate it among patients hospitalized with acute symptomatic pulmonary embolism (PE).<BR><B>METHODS: </B>This prospective cohort study enrolled consecutive stable patients with acute PE who underwent an overnight sleep study within 7 days after diagnosis. Our outcomes were: i) the STOP-Bang questionnaire's utility for risk stratification, ii) the discrimination of the STOP-Bang questionnaire categories, iii) the false negative rate of STOP-Bang questionnaire prediction, and iv) the clinical utility of the STOP-Bang questionnaire to exclude OSA. We also calculated the test performance characteristics to predict OSA.<BR><B>RESULTS: </B>During the study period, 268 patients completed a sleep study. OSA was found in 47% of patients. OSA incidence in low-, moderate-, and high-risk STOP-Bang groups was 22.4%, 48.2%, and 61.5%, respectively (P <0.001). The area under the receiver operating characteristics curve of the STOP-Bang questionnaire for risk of OSA was 0.65. The false negative rate of a low-risk STOP-Bang questionnaire result to rule out OSA was 22.4% and the clinical utility was 21.6%. The sensitivity was 89.8% (97.2% for men and 80.4% for women).<BR><B>CONCLUSIONS: </B>The STOP-Bang questionnaire showed poor discrimination for the risk of OSA in hospitalized patients with acute symptomatic PE. It had a high false negative rate and a low clinical utility. The STOP-Bang questionnaire had a good sensitivity in men, and might be used to rule out OSA in this population.