%0 Journal Article
%T Two new compounds isolated from the aerial parts of gastrodia elata blume.
%A Du C
%A Wang W
%A Wei C
%A Yang W
%A Cheng L
%A Hou Y
%A Liu X
%A Zhu G
%A Li X
%A Xu J
%J Nat Prod Res
%V 0
%N 0
%D 2024 Jul 11
%M 38992980
%F 2.488
%R 10.1080/14786419.2024.2364238
%X Two new aromatic compounds, namely gastupdin A (1), and gastupdin B (2), together with three known compounds, arundin(3), phomosines B (4) and monocillin IV (5), were isolated from the aerial parts of Gastrodia elata Blume. The structures of the new compounds were confirmed through spectral analyses including NMR, HR-ESI-MS, ECD, UV, and IR. All isolated compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death in Human Neuroblastoma Cells, with curcumin as the positive control, however, the activity of all compounds was weaker than the positive control, showing no significant activity.