%0 Case Reports
%T Underdosed generic specialty medications: A prescription for patient harm?
%A Okuda DT
%A Burgess KW
%A Moog TM
%A Patel MA
%J Mult Scler Relat Disord
%V 88
%N 0
%D 2024 Aug 5
%M 38991404
%F 4.808
%R 10.1016/j.msard.2024.105760
%X The use of generic specialty medications amongst individuals with multiple sclerosis (MS) has expanded due to an increase in the number of available agents. We describe a woman who was denied continued use of brand name teriflunomide (AubagioⓇ), despite being clinically stable for 2.5 years, and switched to generic teriflunomide. She experienced a significant spinal cord exacerbation within a few months of starting treatment. We analyzed 3 generic teriflunomide agents, including the one used for treatment, in addition to AubagioⓇ. The generic teriflunomide used by our patient contained 55.5 % content of the labeled amount, well below U.S. FDA specifications.