%0 Journal Article
%T Quercetin in Oncology: A Phytochemical with Immense Therapeutic Potential.
%A Kamal R
%A Paul P
%A Thakur S
%A Singh SK
%A Awasthi A
%J Curr Drug Targets
%V 0
%N 0
%D 2024 Jul 10
%M 38988154
%F 2.937
%R 10.2174/0113894501292466240627050638
%X Quercetin is a natural flavonoid with various pharmacological actions such as anti-inflammatory, antioxidant, antimicrobial, anticancer, antiviral, antidiabetic, cardioprotective, neuroprotective, and antiviral activities. Looking at these enormous potentials, researchers have explored how they can be used to manage numerous cancers. It's been studied for cancer management due to its anti-angiogenesis, anti-metastatic, and antiproliferative mechanisms. Despite having these proven pharmacological activities, the clinical use of quercetin is limited due to its first-- pass metabolism, poor solubility, and bioavailability. To address these shortcomings, researchers have fabricated various nanocarriers-based formulations to fight cancer. The present review overshadows the pharmacological potential, mechanisms, and application of nanoformulations against different cancers.