%0 Journal Article
%T Pathological Findings of Embolus Retrieved by Mechanical Thrombectomy in Cerebral Embolism with Libman-Sacks Endocarditis: A Report of Two Cases.
%A Kodera H
%A Sakamoto Y
%A Aoki J
%A Kimura R
%A Matsumoto N
%A Nishiyama Y
%A Kunugi S
%A Kimura K
%J Intern Med
%V 0
%N 0
%D 2024 Jul 11
%M 38987192
%F 1.282
%R 10.2169/internalmedicine.3212-23
%X Libman-Sacks endocarditis is an important cause of embolic stroke in systemic lupus erythematosus, although the detailed pathogenesis of stroke remains unclear. We herein report two cases of stroke with Libman-Sacks endocarditis in which the emboli were retrieved by mechanical thrombectomy. The embolus consisted of eosinophilic homogeneous acellular structures, whereas fibrin-platelet thrombi were hardly observed in the embolus. Immunohistochemistry showed immunoglobulin deposits in the embolus, suggesting that immunological mechanisms were involved in the growth of the embolus. A pathological analysis of the embolus retrieved by mechanical thrombectomy provided useful information on the etiology, leading to optimal treatment.