%0 Case Reports %T Exploring the Co-occurrence of dermatophyte infection and ichthyosis: A report of 3 cases. %A Magnaterra E %A Difonzo EM %A Magliulo M %A Berti SF %A Gola M %A Pisano L %J J Mycol Med %V 34 %N 3 %D 2024 Jul 7 %M 38986424 %F 3.746 %R 10.1016/j.mycmed.2024.101498 %X Dermatophyte infections frequently pose diagnostic challenges, especially when occurring alongside ichthyosis, a genetic skin disorder characterized by dry, thickened, scaly skin. This case series outlines three cases where dermatophyte infections overlapped with ichthyosis, emphasizing the complexities in clinical identification and differential diagnosis. Atypical clinical presentations in these cases led to initial misdiagnoses. Ichthyosis, a genetic skin disorder characterized by thickened and scaly skin, creates an environment conducive to dermatophyte settlement, complicating the diagnostic process. The cases highlight the importance of considering fungal infections, even when clinical features deviate from the expected course. A vigilant diagnostic approach, including mycological examinations, is crucial for accurate identification and timely management.