%0 Journal Article %T A Case of Polyserositis, Chylous Ascites and Hepatitis Induced by Immune Checkpoint Inhibitors. %A Castelli M %A Betelli M %A Valenti A %A Merelli B %A Loglio A %A Viganò M %A Benetti A %J Eur J Case Rep Intern Med %V 11 %N 7 %D 2024 %M 38984185 暂无%R 10.12890/2024_004237 %X We describe a rare case of polyserositis with chylous ascites following nivolumab therapy, highlighting the challenges in recognising and managing immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICPIs). Induced polyserositis and chylous ascites are very rare and require immunosuppressive treatment, with a variable response of high-dose IV steroids.
CONCLUSIONS: Oncological therapy with immune checkpoint inhibitors (ICPIs) is frequently associated with immune-related adverse events (irAEs) most involving cutaneous, gastrointestinal and pulmonary sites.