%0 Case Reports
%T SMARCB1/INI1-deficient undifferentiated tumour of the thorax: a case report and review of the literature.
%A Zagni M
%A Marando A
%A Negrelli M
%A Lauricella C
%A Motta V
%A Paglino G
%A Veronese S
%A Valtorta E
%A Bonoldi E
%A Pelosi G
%J Pathologica
%V 116
%N 3
%D 2024 Jun
%M 38979590
暂无%R 10.32074/1591-951X-955
%X The 5th WHO classification of thoracic tumours includes thoracic SMARCA4-deficient undifferentiated tumour (SMARCA4-UT) among the "other epithelial tumours of the lung" chapter. Herein, we present a case of undifferentiated thoracic neoplasm with retention of SMARCA4 expression, lack of NUT fusion protein and loss of SMARCB1/INI1 expression. After presenting the clinical and pathological features of the tumour, we carried out a review of the literature on the same topic. Albeit very rare, we believe this entity should be included in the heterogeneous group of undifferentiated neoplasms of the thorax.