%0 Case Reports %T A Rare Case of Retroperitoneal Tumefactive Fibroinflammatory Lesion Related to IgG4-Sclerosing Disease. %A Nikas S %A Zonitsa S %A Anastasiadis P %A Veniadou K %A Roumelioti S %A Mitsas AC %A Gerasopoulos G %A Gkouvis P %J Cureus %V 16 %N 6 %D 2024 Jun %M 38978945 暂无%R 10.7759/cureus.61968 %X We present a unique case of a retroperitoneal tumefactive fibroinflammatory lesion related to IgG4-sclerosing disease; it is a rare manifestation of the IgG4-related disease, which usually causes diffuse fibrosis when located in the retroperitoneum, rather than mass-like lesions. A 49-year-old man presented to the emergency department complaining of abdominal pain and vomiting. Subsequent testing with abdominal ultrasound, CT, and MRI revealed a large retroperitoneal mass of unknown origin, heterogenous, with a concentric circles pattern best visualized in MRI. The lesion was resected, and the histological and immunohistochemical studies revealed an IgG4-related tumefactive fibroinflammatory lesion of the retroperitoneum.