%0 Journal Article
%T Aframomumlabdane, a new bislabdane diterpenoid from Aframomum arundinaceum (zingiberaceae).
%A Ango PY
%A Ghoda AW
%A Abega DF
%A Mapitse R
%A Kuete V
%A Ngadjui BT
%A Fotso GW
%A Kapche DWFG
%J Nat Prod Res
%V 0
%N 0
%D 2024 Jul 8
%M 38976503
%F 2.488
%R 10.1080/14786419.2024.2372847
%X A previously undescribed bislabdane diterpenoid namely aframomumlabdane (1), was isolated from the seed of Aframomum arundinaceum together with seven known compounds (2 - 8). Their structures were established based on a comprehensive analysis of HR-ESI-MS, in conjunction with their 1D and 2D-NMR data. Compound 1 was evaluated for its cytotoxic activity against four cancer cell lines: A549, HepG2, SPC212 and DLD-1. The best activity was observed against SPC212 lung cancer cell line with an IC50 value of 0.52 μM.