%0 Case Reports %T EGFR-TKI-induced Factor V deficiency in a patient with advanced non-small cell lung cancer: The first case report. %A Yoshizaki C %A Yoshida Y %A Nohmi S %A Go Y %A Kusakado R %A Kawamura S %A Inoue D %A Kabasawa N %A Yamaguchi F %J Lung Cancer %V 194 %N 0 %D 2024 Aug 1 %M 38970909 %F 6.081 %R 10.1016/j.lungcan.2024.107869 %X Osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is routinely prescribed as first-line therapy for advanced non-small cell lung cancer, regardless of the presence of the T790M resistance mutation. This study reports a rare case of Factor V inhibitor detection during osimertinib therapy in a patient with lung adenocarcinoma. These findings underscore the importance of vigilant monitoring for coagulation abnormalities during EGFR-TKI therapy.