%0 Journal Article
%T [Guillain-Barre syndrome after allogeneic hematopoietic stem cell transplantation: a case report and literature review].
%A Shi YJ
%A Han Y
%A Wang Y
%A Zhou R
%A Song R
%A Mao DF
%A Xi R
%A Bai H
%A Wu T
%J Zhonghua Xue Ye Xue Za Zhi
%V 45
%N 5
%D 2024 May 14
%M 38964928
暂无%R 10.3760/cma.j.cn121090-20231020-00222
%X Guillain-Barre syndrome rarely develops after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and only a few reports exist in China. Guillain-Barre syndrome is an acute and life-threatening condition that requires early diagnosis and treatment. A patient with acute myeloid leukemia underwent allogeneic HSCT for >5 months and gradually developed limb muscle weakness and limited eye movement after coexisting with delayed acute intestinal graft-versus-host disease. After the examination of cerebrospinal fluid and electromyography, the diagnosis of Guillain-Barre syndrome was confirmed. After a high-dose intravenous immunoglobulin (IVIg) treatment, muscle strength gradually recovered, and the prognosis was good.<BR>异基因造血干细胞移植后合并吉兰-巴雷综合征较为罕见，国内报道很少。吉兰-巴雷综合征发病急，严重威胁患者生命，需尽早诊断及治疗。1例急性髓系白血病患者行异基因造血干细胞移植后5个月余，合并迟发急性肠道移植物抗宿主病后逐渐出现四肢肌无力、眼球运动受限，经脑脊液、肌电图等检查，明确诊断吉兰-巴雷综合征，经大剂量静脉免疫球蛋白治疗，肌力逐渐恢复，预后良好。.